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Cerebellar degeneration and ocular myasthenia gravis in a patient with recurring ovarian carcinoma

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Abstract

Myasthenia gravis (MG) and paraneoplastic cerebellar degeneration (PCD) are immune-mediated syndromes that can represent paraneoplastic disorders. We report a patient with history of ovarian carcinoma that presented with ptosis, diplopia and gait ataxia. Neurophysiological examination and laboratory tests revealed the presence of MG and PCD. An integrated FDG-PET/contrast-enhanced CT scan showed tumor recurrence. This is to the best of our knowledge the first association of MG and PCD with recurring ovarian carcinoma.

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Acknowledgments

We thank Dr. Stefano Bartoletti for his technical supervision.

Conflict of interest statement

The authors declare no competing interest.

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Authors and Affiliations

  1. Neurology Department, Istituto di Neurologia, Università Cattolica del Sacro Cuore, Pol. “A: Gemelli” Largo Gemelli 8, 00168, Rome, Italy

    Pietro Caliandro, Marco Luigetti, Enzo Ricci, Massimiliano Mirabella, Pietro Attilio Tonali & Luca Padua

  2. Fondazione Don Carlo Gnocchi, Rome, Italy

    Pietro Caliandro, Pietro Attilio Tonali & Luca Padua

Authors
  1. Pietro Caliandro
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  2. Marco Luigetti
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  3. Enzo Ricci
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  4. Massimiliano Mirabella
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  5. Pietro Attilio Tonali
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  6. Luca Padua
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Corresponding author

Correspondence to Pietro Caliandro.

Additional information

P. Caliandro and M. Luigetti contributed equally to this work.

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Caliandro, P., Luigetti, M., Ricci, E. et al. Cerebellar degeneration and ocular myasthenia gravis in a patient with recurring ovarian carcinoma. Neurol Sci 31, 79–81 (2010). https://doi.org/10.1007/s10072-009-0154-3

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  • DOI: https://doi.org/10.1007/s10072-009-0154-3

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